Emotional support and counseling may help you and your loved ones deal with the uncertainties and restrictions of this disorder. The experience of ME/CFS varies from person to person. Treatments that are expensive or potentially harmful should be avoided. Patients with this condition may be sensitive to medications, including herbal products and supplements. Many alternative therapies have been promoted for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), but very few have evidence that they work. Sleep apnea can be treated by using a machine that delivers air pressure through a mask while you sleep. ![]() ![]() Your health care team might suggest avoiding caffeine or changing your bedtime routine. Lack of sleep can make other symptoms more difficult to deal with. It may help to keep a daily diary of your activities and symptoms, so you can track how much activity is too much for you. As you improve, you may be able to safely engage in more activity without triggering post-exertional malaise. The goal of pacing is to reduce post-exertional malaise, rather than getting back to the same activity level you had when you were healthy. The goal is to remain active without overdoing it. People who have post-exertional malaise often struggle to find a good balance between activity and rest. It usually begins within 12 to 24 hours after the activity, and it can last for days or weeks. People with ME/CFS have a worsening of their symptoms after physical, mental or emotional effort. Low doses of some antidepressants also can help improve sleep and relieve pain. Treating your depression can make it easier for you to cope with the problems associated with having a chronic disease. Many people with long-term health problems, such as ME/CFS, are also depressed. Medications to regulate blood pressure or heart rhythms may be helpful. Some people with this condition, particularly adolescents, feel faint or nauseated when they stand or sit upright. These include pregabalin (Lyrica), duloxetine (Cymbalta), amitriptyline or gabapentin (Neurontin). If medicines such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve) don't help enough, prescription drugs sometimes used to treat fibromyalgia might be options for you. Some problems associated with ME/CFS can be improved with certain medicines. The most disruptive or disabling symptoms should be addressed first. There is no cure for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). These symptoms must last for at least six months and occur at least half the time at moderate, substantial or severe intensity.
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